Drug Delivery and Disposition. Department of Pharmaceutical and Pharmacological Sciences. KULeuen. Belgium.
Patrick Augustijns has a Pharmacy degree, a Master in Medical Sciences and a Ph.D. in Pharmaceutical Sciences. Prior to becoming a professor at the University of Leuven (Belgium), he performed postdoctoral research at the University of Kansas and at GSK (North Carolina). In 2003, Patrick Augustijns became chairman of Drug Delivery and Disposition. The laboratory has a strong track record in the biorelevant profiling of intestinal drug absorption, covering all underlying processes including dissolution, precipitation, degradation and permeation. For this purpose, a wide range of simulation models is available, including the in vitro Caco-2 cell culture system, the Ussing chamber system and the in situ intestinal perfusion system. In addition, Drug Delivery and Disposition is able and licensed to perform whole animal absorption and pharmacokinetic experiments. Physiology-based pharmacokinetic modelling is available to extrapolate experimental data to human pharmacokinetics. One of the lab’s major research topics involves the bio-relevant and predictive evaluation of absorption-enabling strategies, including solubilization and supersaturation of poorly soluble drugs. In this respect, Drug Delivery and Disposition has elaborated a ground-breaking approach for evaluating intraluminal drug and formulation behavior in humans, which involves the aspiration and in-depth characterization of gastrointestinal fluids. All absorption studies are supported by well-developed analytical equipment (LC-UV, -fluo, -MS/MS) to assess concentrations of drugs, excipients and endogenous compounds in biological matrices. Patrick Augustijns is (co)author of ± 310 (peer reviewed) papers in international journals and more than 300 presentations at scientific meetings. Since 2008, Patrick Augustijns is AAPS-fellow.
María Carmen Collado
Research Scientist. IATA-CSIC. Department of Biotechnology. Valencia. España.
M. Carmen Collado, PhD in Biotechnology (2005, Polytechnic University of Valencia-UPV, Valencia, Spain); Adjunct Professor at the University of Turku, Finland and Research Scientist at Dept. Biotechnology, Institute of Agrochemistry and Food Technology-Spanish National Research Council (IATA-CSIC), Valencia, Spain. Her research work is multidisciplinary and includes microbiology, food science and nutrition areas. Her interests are focused on probiotics, microbiota and health and nutrition during pregnancy and early life period. Her current work includes basic and applied research on molecular analysis and evaluation of health effects of beneficial bacteria and probiotics, the microbial-host interactions, microbiome and its role in human health and diseases and also, the influence of perinatal factors during early life.
Researcher ID: H-4924-2012 (http://www.researcherid.com/rid/H-4924-2012)
Research professor in food technology
Kaisa Poutanen, DSc (Tech) from Helsinki University of Technology (now Aalto University) and invited honorary doctor in food sciences at University of Helsinki, Research Professor in food technology at VTT Technical Research Centre of Finland. She has extensive track record in connecting food technology and nutrition sciences. Her research has dealt with development and nutritional physiology of healthy plant based foods, with focus on bioprocessing of cereals, functionality of dietary fibre and bioavailability of phytochemicals. She has coordinated many international multidisciplinary consortia, including the large European project Healthgrain, was founder of Healthgrain Forum and is fellow of International Association for Cereal Science and Technology and of AACC International.
María Carmen Collado